by 
The Curious Bag
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Depressants cause chemicals in your brain to slow down, and interfere with brain cell communication and function. Ingesting two depressant substances can create heightened problems---physically and mentally.
Symptoms
Semcaprevention.org notes that large doses of depressants can cause poor coordination, slurred speech, and impaired judgment and breathing.
Considerations
Mixing two depressants can result in coma or even death, reports semcaprevention.org. Patients should mix drugs only under the guidance of a physician.
Types
Depressants include alcohol, over-the-counter cold remedies, prescription medications and street drugs.
Use
Depressants, when appropriately used, relieve problems such as anxiety, panic attacks and depression. Such medication requires a prescription.
Abuse
According to semcaprevention.org, heavy and/or regular use of some medications can cause the body to develop a tolerance, requiring more of the depressant to feel the same effects or benefits.
Warning
Depending on the length of time between consumption of the two depressants, suddenly stopping can result in shock or seizures, reports semcaprevention.org.
Source:
SEMCA Prevention: Know the Facts about Depressants and Painkillers
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