Dosulepin is an antidepressant of the tricyclic family, in lower dosages its used for anxiety and chronic pain (in lower dosages for chronic pain). There are alternative drugs out there, depending on what you are taking Doseulepin for. If it is for chronic pain (which I assume) there is/are other choices. Few considering liver issues. If sleep loss is unbearable, you might want to speak with your doctor about going back on the Doseulepin and then weaning off of it over time. I do not know how this stacks against your liver condition. I'm currently taking amitriptyline which is of the same class of drugs. I know with that I started at 10 mg and worked up to 30 mg over a period of 2 weeks - to stop I would have to do that in reverse, lowering the dosage to 20 mg for a week, then 10 mg for a week before stopping. If I just stop it will really play havoc with my sleeping schedule - BTW I already have enough trouble sleeping. LOL I would suggest trying 'herbal' or 'homeopathic' remedies. For instance drinking catnip and chamomile tea. Although in cats catnip is an 'upper' in humans its a 'downer' a relaxant. A 1 to 1 ratio of chamomile leaves to catnip leaves works best. You use a teaspoon of the combined leaves per cup of tea. You DO NOT use sugar, you use honey (which also contains tiny amounts of chemicals which relax humans). I use a mix of 'sleepy time' tea bags and I have a tea ball/strainer which is a metal ball with holes - I put half a teaspoon of catnip in the ball, and seep both the ball and the bag together for 5 minutes. I make a 'strong' cup of tea. I have hot tea in winter and cold tea in summer. In summer I make it up by the gallon, I boil two cups of water, turn off the pot throw in 3 teaspoons of loose catnip, and 4 bags of sleepy time. I let it sit on the stove until its room temperature, then I use a coffee filter to strain out the loose tea as I pour the tea water into the gallon container. I fill with cold water and use a couple three tablespoons of honey. Sound therapies (listening to a track of rain or ocean waves over and over again) can induce a 'trance-like' state which is simply deep relaxation which can lead to a better nights sleep. I'm assuming you have chronic pain issues, or are in physical pain, dealing with that through relaxation methods and through using a heating pad on a timer may make sleep come easier. For my knee I have the heating pad plugged into a timer - The timer is set to turn off an hour after I go to bed. I find that laying down and laying the heating pad on top of my knee set on low, tends to ease the pain enough for me to go to sleep 'soonish' 20 or 30 minutes or so. You are not supposed to lay on top of a heating pad, and you really do not want to leave it on all night long - it can do weird things to muscles - causing a 'cold' in the muscle the next day.