Ask a question about Vocal problems Can an antidepressant such as Zoloft cause a change in the voice?
by 
christyfour
ANSWERS: 3
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Any change of mood can cause a marked change in the voice. It doesn't need to be drug induced.
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I was prescribed Zoloft a few years ago, so I started reading all the adverse reactions. I don't recall anything related to the voice. Maybe, because of the depressive state of mind, the voice sounds different, probably a little slow and weak. What Zoloft did to me was to take away my sexuality. I was a 43 year old male, and while taking Zoloft I became like a little kid...No sexuality of any kind...So, I threw them away and my Doctor tried Wellbutrin. It works great on me.
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Almost any kind of drug you put into your bloodstream will affect your voice. Some positively, some negatively. As a singer for over 50 years, I wouldn't touch Zoloft, but your reaction to it might be different. I've found that most antidepressants, stress-relievers and anxiety medicines have effects that I don't want while I'm onstage. Minor, yes, but, if you're a singer who knows every facet of your voice, it could affect the way you perform. If you're good enough at what you do, you won't need Zoloft, or anything but the music. Music is the best drug there is.
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