ANSWERS: 1
  • Lorazepam (first marketed under the brand names Ativan® and Temesta®) is a benzodiazepine type drug. As a benzodiazepine, lorazepam possesses all five principal benzodiazepine actions (sedative/hypnotic, muscle relaxant, anxiolytic, amnestic and anticonvulsant), but to different extents. Lorazepam also has found use as an adjunct anti-nausea drug. Lorazepam is a potent drug and its unique pharmacological properties underlie both its drawbacks and its advantages. Clorazepate (marketed under the brand names Tranxene® and Tranxilium®) is a drug which is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative and skeletal muscle relaxant properties. Clorazepate is available in 3.75, 7.5, and 15 mg capsules or tablets. An oral dose of 2mg lorazepam will result in a total serum lorazepam level of around 20nanograms/ml, half of which is lorazepam and half its inactive metabolite, lorazepam glucuronide.

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