Interactions A case of refractoriness to furosemide has been reported in a patient receiving ginseng. Ginseng may elevate plasma concentrations of nifedipine, increasing therapeutic and adverse effects. Manic-like symptoms, headache, and tremulousness were reported during concurrent use of phenelzine and ginseng. Ginseng has been reported to decrease the anticoagulant effect of warfarin. Patients taking these drugs should be cautioned to avoid ginseng and advised to consult their health care provider before taking herbal products. Side Effects The most common adverse reactions with ginseng are nervousness and excitation. However, there have been reports of diffuse mammary nodularity and vaginal bleeding. A hypoglycemic effect has also been documented. Postmarketing surveillance of CVT-E002 in Canada from 1996 to 2006 led to 100 documented adverse reaction reports, out of over 200 million doses of CVT-E002 sold. Reactions included abdominal pain, confusion, diuresis, dizziness, drowsiness, headache, insomnia, joint pain, lowered blood pressure, nausea, and vomiting. http://www.drugs.com/npc/ginseng.html Some further reading http://www.itmonline.org/arts/ginseng.htm http://www.medscape.com/viewarticle/482833 Might find this interesting http://nccam.nih.gov/health/asianginseng/#intro This one has some extra details http://www.zhion.com/GINSENG.html