ANSWERS: 3
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The contraceptive pill (combining estrogen and progesterone) was aproved for contraceptive use in the United States in 1960.
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It was developed in the 1950's and approved by the FDA as a contraceptive in the 1960's. Go here for a full timeline: http://www.pbs.org/wgbh/amex/pill/timeline/timeline2.html
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In the seventies they reduced the dosage by some 400 percent. Early dosages were a tad off. Google Thalidomide babies.
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