I Have a 1987 Ford F150 with 5.0 V8, Can the TFI ignition module be removed without removing the distributor

you can remove your ignition modual without removing the distributer buy a tool for this at the auto parts store a socket wont fit in the screw holes in the modual then pull the modual straight down to remove

Service manual says no, you need to pull the distributor. Here are the instructions on how to change the module. See pict for details.

Remove distributor cap and adapter. Position cap and wires aside.
Disconnect TFI wiring.
Remove distributor from engine using tool T82L-12270-A or equivalent to remove security-type hold-down bolt, if equipped.
Place distributor on workbench and remove 2 TFI module screws, Fig. 2.
Pull right side of module down distributor mounting flange and then back up to disengage module terminals from connector in distributor base. Module may then be pulled toward flange and away from distributor. Do not attempt to lift module from mounting surface before moving entire TFI module toward distributor flange, as pins at distributor/module connector will break otherwise.
Coat metal base plate of TFI ignition module with 1/32 inch thick layer of silicone grease D7AZ-19A331-A, or equivalent.
Place TFI module on distributor base mounting flange. Carefully position TFI module assembly toward distributor bowl and securely engage 3 distributor connector pins.
Install 2 TFI module mounting screws and torque to 9---35 inch lbs.
Install distributor on engine.
Install distributor cap and adapter.
Connect TFI wiring.
Check and, if necessary adjust engine timing according to decal.

no. you gotta pull off the distributor to get at the bolts for the TFI ignition module

I don't believe you can change it without pulling the distributor. I've changed 3 of these on my 87 F150 & have the correct tool from the parts house. But no matter how you try, it just can't be done without pulling out the whole distributor. Even the shop manual tells you that it must be removed in order to change the module. I've got to go outside in the middle of a field in sub freezing tempatures (maybe 10 or 12 degrees) tomorrow to change it again. It's going to be big fun............the old point type ignitions didn't give enough problems & were too easy to work on if & when they did. So, they came up with this module junk & computor junk.........