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by meizzjburks56 on July 27th, 2005

meizzjburks56

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What is in the Depo-Provera injection that causes weight gain?

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Answers. 2 helpful answers below.

  • by lynnenorth on March 18th, 2006

    lynnenorth

    Estrogen binds to specific receptors on the surface of adipocytes (fat cells) which tells them to grow and divide, so you end up with more fat cells in response to a heavy-duty burst of estrogen.

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  • by VenusxMantrap on November 19th, 2005

    VenusxMantrap

    The hormones cause weight gain

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