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The prostate-specific antigen (PSA) test measures the amount of antigen protein cells in the blood. Doctors use the test to check for prostate cancer, and to look for recurrence in prior cancer patients. An elevated PSA level, however, does not always signify prostate cancer.
Enlarged Prostate
An enlarged prostate, also called benign prostatic hyperplasia (BPH), naturally occurs as men age. The condition does not increase the risk of cancer, but can cause an elevated PSA level.
Digital Rectal Exam (DRE)
A digital rectal exam is often performed to check the prostate gland. It must be done after blood is drawn for the PSA test, since it can raise the PSA level.
Prostatitis
An inflammation of the prostate gland, called prostatitis, can be caused by an infection. The inflammation can cause elevated PSA levels as well as difficulty urinating and pain.
Orgasm
According to Mayo Clinic, PSA levels rise after ejaculation, and may remain higher up to two days.
Lab Variances
The National Cancer Institute reports that test results can vary depending upon the lab where they are processed, which can make levels appear high.
Source:
National Cancer institute: Prostate-Specific Antigen (PSA) Test
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