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The Curious Bag
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Hypoalphapoproteinemia (HA), more commonly known as low high-density lipoprotein (HDL), occurs when HDL cholesterol levels fall below 40 mg/dL for men or 50 mg/dL for women.
Purpose
High-density lipoprotein cholesterol acts as a natural cleanser in the body's blood system by removing excess amounts of LDL, low-density lipoprotein, and carrying it to the liver for disposal.
Symptoms
Hypoalphapoproteinemia itself often does not have symptoms. Many patients with this condition will present with symptoms of related conditions, such as premature atherosclerosis, cerebrovascular disease, xanthomas, or corneal opacification.
Diagnosis
Laboratory tests and imaging studies are common tools in diagnosing low HDL. Typically, only laboratory tests, including plasma lipid profiles and blood tests, are necessary; however, in the case of complications, imaging studies related to the medical conditions occur.
Treatment
Diets high in niacin can raise HDL levels by as much as 15 to 35 percent. Additionally, statins may assist in raising levels by 5 to 10 percent.
Prevention/Solution
Promote high HDL levels by avoiding tobacco products, participating in regular physical activity, and maintaining a healthy weight.
Source:
Low HDL Cholesterol (Hypoalphalipoproteinemia)
American Heath Association: What Your Cholesterol Levels Mean
Resource:
Niacin to boost your HDL, 'good,' cholesterol
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