by 
The Curious Bag
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<h4 class="dechead">On One Hand: Dosage is dependent on different variables
Aspirin comes in low-dose (81 mg) tablets, regular-dose (325 mg) tablets, and extra-strength (500 mg) tablets and caplets, meaning that dosage and frequency of administration varies depending on the type of tablet or caplet. The amount and frequency of dosage will also depend on the severity of the symptoms.
On the Other: Upper limits are clear
Although there are ranges of doses of aspirin, dosage information clearly states that patients should not exceed 4,000 mg (4 grams) in a 24-hour period. This amount translates to 48 low-dose tablets, 12 regular-dose tablets or eight extra-strength tablets.
Bottom Line
Take four to eight low-dose tablets every four hours. For regular-strength tablets, take one or two tablets every four hours, or three tablets every six hours. For extra-strength caplets, take one or two caplets every four to six hours.
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