Hehe great question! Let's see... You could have TNT or C4 or other explosives go off in your hand, and after the smoke clears you'd still be alive, just having to brush off some black soot and maybe have some burned hair or something which would easily wash away. You could have an anvil, boulder, ocean liner or other massive object drop on you and live to tell about it. You could be hit in the head with a huge sledgehammer and have your skull be deformed but then magically bounce back to normal shape after a few seconds. You could take a massive electric shock and just light up, with your bones showing in flashes like a huge x-ray had been taken, and survive with some smoke emerging from your ears. If you jumped off a bridge or cliff, you'd survive the fall and be able to hold up a flag or sign saying "OUCH!" from down inside the crater you make.

Those poor pharmaceutical companies who sell pain medications would go out of business. lol In fact, no need for hospitals, doctors, medical/health industry altogether .. since cartoon characters are ageless. No aging related illnesses .. no terminal illnesses .. and any "bangups" are temporary and totally reversable - without need for drugs, splints or operations. More people might invest in stock or spend money with .. companies like Acme .. so we can chase each other around using whatever creative means we like .. and know we'll all be ok at the end of the day. Things fall on us from the sky? Our bodies flatten down like an accordian. Could even flip to our side and roll around. But eventually, we'll POP back up .. nothing broken .. no bruises .. no bleeding .. good as new. We can eat whatever we want - whenever we want - or not eat at all - and our bodies will remain unchanged - as big or little as the day we were "born". We could get some great views of our towns from the sky if but climb high enough and run off that cliff. But physics "does" kick in briefly as we realize "uh oh" - reality interupts - and we FALL. But we're back on cartoon physics after that since we're OK no matter how far we fall. :)

Every fight would be a rolling dust cloud with random fists and feet sticking out. Getting shot would only require a headband and a crutch. Sticking your finger in the end of a gun would cause it to backfire. You could run over the horizon (over a series of hills) in about 5 seconds flat. You could (and would) get struck by lightning every single time it rained. Great Question Barca :)