ANSWERS: 3
  • You can pass the disease of sickle cell anemia on to your offspring if your partner also has this trait in his genes.
  • People who have sickle cell trait do not usually have any have any of the symptoms of the disease. However, it is possible for someone who has sickle cell trait to have complications,some of these complications are; Dehydration. Low oxygen (when excercising extremely hard). High altitude ( flying). Women with sickle cell disease can have a safe pregnancy. However, there is an increased risk of complications that can affect the health of mother and baby, for example, preterm labour and low birthweight, the pregnancy can be healthy with good prenatal care and careful monitoring throughout the pregnancy. If one person has sickle cell trait and the other parent has normal hemoglobin there is a 1 in 2 chance with each pregnancy that the baby will be born with sickle cell trait. If both parents have sickle cell trait, there is a 1 in 4 chance with each pregnancy that the baby will have sickle cell disease.
  • People with Sickle Cell Trait do not typically display any of the symptoms generally associated with Sickle Cell Anemia. They aren't "sick." They have one gene for normal hemoglobin (HbA) and one gene for sickle hemoglobin (HbS), the genes will be passed to their children. This trait, Sickle Cell Trait, is selected for and does not die out because it affords significant protection against malaria. Because the red blood cells in a person with Sickle Cell Trait are normal,they are not eliminated from the body. However, when infected with the plasmodium parasite which causes malaria, oxygen tension is reduced and the cells sickle. Since sickle cells are removed from the circulation and destroyed, selective sickling of infected sickle trait red cells would reduce the parasite burden in people with sickle trait. These people would be more likely to survive acute malarial infections.

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