Wikipedia gives some good possibilities: The origins of the word are unknown. The Oxford English Dictionary (OED) says that the word puss is common to several Germanic languages, usually as a call name for the cat — not a synonym for cat, as it is in English. The OED and Webster's Third International Dictionary point out similarities with words including:- Old Norse, pÅ«ss (pocket) Old Saxon pÅ«se (vulva) Old English pusa (bag) The medieval French word pucelle referred to a young adolescent girl or a virgin, although this comes from a slang term for virginity puce (= flea) rather than referring to cats (but cf. French chatte (female cat), a current vulgarism for the female pudenda). In the 17th century, the term was also used to refer to women in general. Philip Stubbs, an English pamphleteer, wrote in his 1583 book "The Anatomie of Abuses" that "the word pussie is now used of a woman". It has been informally suggested in folk etymology that it is a shortened form of the word "pusillanimous" which is defined by the Oxford English Dictionary as "showing a lack of courage or determination" or cowardly. This meaning would seem to be consistent with the intention of the word "pussy" when used as an insult toward a man. This term, however, comes from the Latin words pusillus (petty) and animus (spirit) and is unrelated to the Germanic derivations of puss and pussy. Uses Cat and similar According to the Oxford English Dictionary, puss was used as a "call-name" for cats in both German and English, but pussy was used in English more as a synonym for "cat": compare "pussycat". In addition to cats, the word was also used for rabbits and hares as well as a humorous name for tigers. In the 19th century, according to the Oxford English Dictionary, the meaning was extended "in childish speech, applied to anything soft and furry", as in pussy willow. In thieves' slang, it meant "fur coat". To pussyfoot around the question or point means to be evasive, cautious, or conceal one's opinions. The reference is to the careful soft tread of the cat and has no vulgar implications, other than obvious ties to weakness, which "pussy" sometimes connotes. ============== From the above information, there may be a connection between the word used for a cat and the word used for female genitalia.