Features

Frontline Plus contains two active ingredients: fipronil, a chemical that kills adult fleas, and (S)-methoprene, a chemical that prevents flea eggs from hatching.

Concerns

While (S)-methoprene is only toxic to fleas, there are some valid concerns with fipronil.

Effects

Fipronil can cause skin irritations, redness, itchiness, scaliness and hair loss at the application site. If ingested, excessive drooling and vomiting may result. Some animals will act depressed or show nervous-system irregularities. These effects are usually temporary.

Treatment

If you suspect that your pet is experiencing an adverse reaction to Frontline, bathe him immediately with soap and warm water, and rinse thoroughly. Consult your veterinarian for further advice.

Prevention

There are steps you can take to prevent Frontline overdose in your pet. Always purchase the right formula and size for your pet. Read and follow all label directions carefully.

Bottom Line

Frontline overdoses are very rare, and no serious side effects have been found, even at five times the correct dosage. However, any individual can have a reaction to any medication, so use caution when applying Frontline Plus to your pet.

Source:

The Use of Fipronil (Frontline Top Spot) in Dogs and Cats

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