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Onychomycosis is typically quite difficult to cure completely. Even if a clinical cure is achieved after long therapy with either topical or oral drugs, normal regrowth takes four to six months in the fingernails, and eight to 12 months in the toenails, which grow more slowly. Relapse is common, and often, the nail or nail bed is permanently damaged. For toenails infected with onychomycosis, terbinafine seems to offer the highest cure rate (35–50%). Itraconazole cure rates typically range from 25–40%, and those with fluconazole, which was recently approved in the United States, have not been documented by long-term trials
Source: The Gale Group. Gale Encyclopedia of Medicine, 3rd ed.";

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