Homeopathic acute prescribing is not recommended for the treatment of chronic conditions requiring constitutional prescribing, for severe infections requiring antibiotic treatment, or for conditions requiring major surgery. It is also not recommended for the treatment of mental health problems.

Persons who are treating themselves with homeopathic remedies should follow professional guidelines regarding the limitations of home treatment. Most homeopathic home treatment guides include necessary information regarding symptoms and disorders that require professional attention.

Homeopathic remedies may lose their potency if used at the same time as other products. Some homeopathic practitioners recommend the avoidance of mint and mentholated products (toothpastes, candies, chewing gum, mouth rinses), as well as camphor and camphorated products (including eucalyptus and Tiger Balm), patchouli and other essential oils, moth balls, strong perfumes, aftershaves, scented soaps, stress, x rays, coffee, nicotine, recreational drugs (marijuana) and certain therapeutic drugs (most notably cortisone and prednisone) during treatment. Patients are also advised to avoid electric blankets and dental work, as these are thought to adversely affect homeopathic therapy. Homeopathic remedies should never be placed near magnets.

Practitioners caution that high-potency preparations should be used only under the supervision of a homeopathic practitioner.