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    ERS complications are related either to the drugs used during the procedure, or the results of dye injection or cutting of tissue. The overall complication rate is 5–10%. During the exam, the endoscopist can cut or stretch structures (such as the muscle leading to the bile duct) to treat the cause of the patient's symptoms. Cutting or stretching of these structures can sometimes cause a hole or perforation. The use of sedatives also carries a risk of decreasing cardiac and respiratory function, however, it is very difficult to perform these procedures without these drugs.

    Other major complications related to ERCP or ERS are pancreatitis (inflammation of the pancreas) and cholangitis (inflammation of the bile ducts). Bacteremia (the passage of bacteria into the blood stream) and bleeding are also risks.

    Source: The Gale Group. Gale Encyclopedia of Medicine, 3rd ed.";

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