ANSWERS: 1
  • <div class="section1"> Definition

    Cardiomyopathy is an ongoing disease process that damages the muscle wall of the lower chambers of the heart. Congestive cardiomyopathy is the most common form of cardiomyopathy. In congestive cardiomyopathy, also called dilated cardiomyopathy, the walls of the heart chambers stretch (dilate) to hold a greater volume of blood than normal. Congestive cardiomyopathy is the final stage of many heart diseases and the most common condition resulting in congestive heart failure.

    Description

    About 50,000 Americans develop cardiomyopathy each year. Of those, 87% have congestive cardiomyopathy. Primary cardiomyopathy accounts for only 1% of all deaths from heart disease.

    When the heart muscle is damaged by a disease process, it cannot pump enough blood to meet the body's needs. Uninjured areas of the walls of the two lower heart chambers (called ventricles) stretch to make up for the lost pumping action. At first, the enlarged chambers allow more blood to be pumped with less force. The stretched muscle can also contract more forcefully. Over time, the heart muscle continues to stretch, ultimately becoming weaker. The heart is forced to work harder to pump blood by beating faster. Eventually it cannot keep up, and blood backs up into the veins, legs, and lungs. When this happens, the condition is called congestive heart failure.

    Congestive cardiomyopathy usually affects both ventricles. Blood backed up into the lungs from the left ventricle causes fluid to congest the lung tissue. This is called pulmonary edema. When the right ventricle fails to pump enough blood, blood backs up into the veins causing edema in the legs, feet, ankles, and abdomen.

    Causes and symptoms

    Congestive cardiomyopathy may be caused by a number of conditions. Cardiomyopathy with a known cause is called secondary cardiomyopathy. When no cause can be identified, it is called primary cardiomyopathy or idiopathic cardiomyopathy. About 80% of all cases of cardiomyopathy do not have a known cause. Many heart specialists think that many cases of idiopathic congestive cardiomyopathy may be caused by a viral infection. Because cardiomyopathy may occur many years after a viral infection and viruses sometimes go undetected in laboratory tests, it is difficult to know if a virus is the cause. Some people have a weak heart from advanced coronary artery disease that causes heart muscle damage. This is sometimes called ischemic cardiomyopathy.

    Conditions that can cause congestive cardiomyopathy are:

    • coronary artery disease
    • infections
    • noninfectious inflammatory conditions
    • alcohol and other drugs or toxins
    • hypertension
    • nutritional and metabolic disorders
    • pregnancy

    Coronary artery disease is one of the most common causes of congestive cardiomyopathy. In coronary artery disease, the arteries supplying blood to the heart become narrowed or blocked. When blood flow to an area of the heart is completely blocked, the person has a heart attack. The heart muscle suffers damage when its blood supply is reduced or blocked. Significant recurrent muscle damage can occur silently. This damage can lead to congestive cardiomyopathy.

    Infections caused by bacteria, viruses, and other microorganisms can involve the heart, causing inflammation of the heart muscle (myocarditis). The inflammation may damage the heart muscle and cause congestive cardiomyopathy. In the United States, the coxsackievirus B is the most common cause of viral congestive cardiomyopathy.

    Myocarditis can also be caused by noninfectious disorders. For example, the conditions sarcoidosis, granulomatous myocarditis, and Wegener's granulomatosis cause inflammation and tissue death in the heart muscle.

    Years of drinking excessive amounts of alcohol can weaken the heart muscle, leading to congestive cardiomyopathy. Other drugs and toxins, such as cocaine, pesticides, and other chemicals, may have the same effect.

    High blood pressure (hypertension) puts extra pressure on blood vessels and the heart. This increased pressure makes the heart work harder to pump blood, which may thicken and damage the chamber walls.

    Severe nutritional deficiencies can weaken the heart muscle and affect its pumping ability. Certain disorders of metabolism, including diabetes mellitus and thyroid disorders, can also lead to congestive cardiomyopathy.

    Occasionally, inflammation of the heart muscle and congestive cardiomyopathy may develop late in pregnancy or shortly after a woman gives birth. This type of congestive cardiomyopathy is called peripartum cardiomyopathy. The cause of congestive cardiomyopathy in pregnancy is not known.

    Congestive cardiomyopathy usually is a chronic condition, developing gradually over time. Patients with early congestive cardiomyopathy may not have symptoms. The most common symptoms are fatigue and shortness of breath on exertion. Unfortunately, sudden cardiac death is not uncommon with this condition. It stems from irregular heart rhythms in the ventricles (ventricular arrhythmias).

    Patients with more advanced congestive cardiomyopathy may also have chest or abdominal pains, extreme tiredness, dizziness, and swelling of the legs and ankles.

    Diagnosis

    Diagnosis of congestive cardiomyopathy is based on:

    • symptoms
    • medical history
    • physical examination
    • chest x ray
    • electrocardiogram (ECG; also called EKG)
    • echocardiogram
    • cardiac catheterization

    The diagnosis is based on the patient's symptoms, a complete physical examination, and tests that detect abnormalities of the heart chambers. The physician listens to the heart with a stethoscope to detect abnormal heart rhythms and heart sounds. A heart murmur might mean that the heart valves are not closing properly due to the ventricles being enlarged.

    A chest x ray can show if the heart is enlarged and if there is fluid in the lungs. Abnormalities of heart valves and other structures may also be seen on a chest x ray.

    An electrocardiogram provides a record of electrical changes in the heart muscle during the heartbeat. It gives information on the heart rhythm and can show if the heart chamber is enlarged. An ECG can detect damage to the heart muscle and the amount of damage.

    Echocardiography uses sound waves to make images of the heart. These images can show if the heart wall or chambers are enlarged and if there are any abnormalities of the heart valves. Echocardiography can also evaluate the pumping efficiency of the ventricles.

    Cardiac catheterization usually is only used if a diagnosis cannot be made with other methods. In cardiac catheterization, a small tube (called a catheter) is inserted into an artery and passed into the heart. It is used to measure pressure in the heart and the amount of blood pumped by the heart. A small tissue sample of the heart muscle can be removed through the catheter for examination under a microscope (biopsy). This biopsy can show the type and amount of damage to the heart muscle.

    Treatment

    When a patient is diagnosed with congestive cardiomyopathy, physicians try to find out the cause. If coronary artery disease is not the culprit, in most other cases a cause is not identified. When a condition responsible for the congestive cardiomyopathy is diagnosed, treatment is aimed at correcting the underlying condition. Congestive cardiomyopathy caused by drinking excess alcohol or by drugs or toxins can be treated by eliminating the alcohol or toxin completely. In some cases, the heart may recover after the toxic substance is removed from the body. Bacterial myocarditis is treated with an antibiotic to eliminate the bacteria.

    There is no cure for idiopathic congestive cardiomyopathy. Medicines are given to reduce the workload of the heart and to relieve the symptoms.

    One or more of the following types of medicines may be prescribed for congestive cardiomyopathy:

    • digitalis
    • diuretics
    • vasodilators
    • beta blockers
    • angiotensin converting enzyme inhibitors (ACE inhibitors)
    • angiotensin receptor blockers

    Digitalis helps the heart muscle to have stronger pumping action. Diuretics help eliminate excess salt and water from the kidneys by making patients urinate more often. This helps reduce the swelling caused by fluid buildup in the tissues. Vasodilators, beta blockers, and ACE inhibitors lower blood pressure and expand the blood vessels so blood can move more easily through them. This action makes it easier for the heart to pump blood through the vessels.

    Patients may also be given anticoagulant medications to prevent clots from forming due to pooling of blood in the heart chambers. Medicines to prevent abnormal heart rhythms (arrhythmias) may be given, but some of these drugs can also reduce the force of heart contractions. Automatic implantable cardioverter defibrillators (AICDs) can treat life-threatening arrhythmias, which are relatively common in severe cardiomyopathy.

    Certain lifestyle changes may help reduce the workload on the heart and relieve symptoms. Some patients may need to change their diet, stop drinking alcohol, begin a physician-supervised exercise program, and/or stop smoking.

    Severe congestive cardiomyopathy usually causes heart failure. When the heart muscle is damaged so severely that medicines cannot help, a heart transplant may be the only remaining treatment to be considered.

    Prognosis

    The outlook for a patient with congestive cardiomyopathy depends on the severity of the disease and the person's health. Generally, congestive cardiomyopathy worsens over time and the prognosis is not good. About 50% of patients with congestive cardiomyopathy live for five years after the diagnosis. Twenty five percent of patients are alive 10 years after diagnosis. Women with congestive cardiomyopathy live twice as long as men with the disease. Many of the deaths are caused by sudden abnormal heart rhythms.

    Prevention

    Because idiopathic congestive cardiomyopathy does not have a known cause, there is no sure way to prevent it. The best way to prevent congestive cardiomyopathy is to avoid known causes such as drinking excess alcohol or taking toxic drugs. Eating a nutritious diet and getting regular exercise to improve overall fitness also can help the heart to stay healthy.

    Congestive cardiomyopathy may also be prevented by identifying and treating any conditions that might damage the heart muscle. These include high blood pressure and coronary artery disease. Regular blood pressure checks and obtaining immediate medical care for hypertension and symptoms of coronary artery disease, such as chest pain, are important to keep the heart functioning properly.

    Finally, diagnosing and treating congestive cardiomyopathy before the heart becomes severely damaged may improve the outlook.

    Source: The Gale Group. Gale Encyclopedia of Medicine, 3rd ed.

  • Copyright 2020, Wired Ivy, LLC

    Answerbag | Terms of Service | Privacy Policy