The prescription medication Zegerid is used to treat digestive ulcers, reflux disease (GERD) and erosion of the esophagus. While it has proved effective at treating these conditions, Zegerid poses a risk for side effects in some patients.

Types

Common side effects of Zegerid include abdominal pain, weakness, constipation, diarrhea, flatulence, nausea, vomiting, acid regurgitation and headaches.

Significance

The most common side effects of Zegerid pose little threat for long-term health complications. These common side effects occur in approximately 1 percent to 5 percent of patients, according to FDA clinical trials published by the U.S. National Library of Medicine.

Drug Interactions

When combined with blood-thinning medications, such as warfarin (Coumadin), Zegerid poses an increased risk for sudden hemorrhages or prolonged bleeding after an injury or surgery, according to the U.S. National Library of Medicine. The drug also causes an increased likelihood for side effects from other medications, such as the seizure drug Phenytoin and the anti-anxiety medication diazepam (Valium).

Warning

Zegerid has the potential to cause electrolyte imbalances, including deficiencies of calcium, sodium, potassium and phosphorous, warns the U.S. National Library of Medicine. Use of the drug also increases the risk for bacterial and fungal infections and infrequently leads to respiratory failure, high blood-sugar levels and changes in heart rate or blood pressure.

Considerations

Because the effects of Zegerid upon fetal development are unknown, doctors rarely prescribe it for use in pregnant women. Also, if you have a history of liver disease or electrolyte imbalances, it may not be safe for you to take Zegerid.

Source:

U.S. National Library of Medicine Daily Med: zegerid (omeprazole and sodium bicarbonate) powder, for suspension

Mayo Clinic: Omeprazole (Oral Route)