Depends on what, how much, and in what combination. But almost always not good.

Heart enlarged 1040 g with hypertrophic and dilated ventricles Hypertensive change in coronary arteries and myocardium. Aorta is free of atherosclerotic deposits. Coronary vessels contain mild to moderate hypertensive thickening of the muscular wall

Liver enlarged 4,610 g smooth round edges moderate fatty changes but no increased lobularity or fibrosis
I received: The Autopsy and toxicology report.
My son had Organomegaly they say due to severe obesity.


Spleen enlarged 270 g
0.26 mg/l Amitriptyline
0.08 mg/l Nortriptyline
0.11 mg/l Citalopram
0.08 mg/l hydrocodone
0.011 mg/l alprazolam
Valporic acid
Acetaminophen
Fluoxetine
Norfluoxetine
Trihexylphenidyl
Diazepam
Nordiazepam
Temazepam
Present confirmed

These are just what they found in system but list of meds prescribed below.
No street drug or alcohol noted. Cannabinoid,cocaine, cocaine metabolites
States several drugs found in system all at or below therapeutic levels and these did not contribute to his death

What do they consider several???? All prescribed meds show severe interactions and possible liver & heart symptoms which can occur. Since he was not on one but 17 to 21 How can they not consider this drug induced Cardiomyopathy especially since liver was so enlarged and spleen also became increased in size????? Why after seeing Dr's for over a year did they not find any problems with lab test showing damage being done to organs???

Anything, including nothing, overdose or death.