First of all I would not secretly take hair samples and get it checked. That is bad behavior on your part. It breeds distrust and if they are using will most undoubtedly result in making it harder for them to confront their drug use when they DO catch on to what you did. (You can be certain they will know what you did).
Secondly a change in behavior does not always mean drug use. There are some serious medical conditions, Like brain tumors that can cause change in behavior.
Other things can be stress, trauma, or just run of the mill depression/anxiety. There are many others.
EXAMPLE: Right after 9-11 a lot of people had "changes" not because they were doing drugs but because of Post Traumatic Stress.
Bi-polar people in their manic stage act very similarly to those tweaking (on meth) in their depressed stage they are like a tweaker coming down. The two are very similar in several ways.
Unless you look in their eyes and see dialated pupils, or see them slamming (IV drug use) or snorting or smoking meth DO NOT assume that they are taking meth. Not only do you stand a good chance of being wrong, but you might miss getting a proper diagnoses which could save a life.
Further if they are doing drugs it could be E, coke, Pot, Heroine - there are a lot of drugs out there and accusing an addict of taking a drug they are not can lead to more serious troubles. The mind plays tricks, thus a pot smoker will think and believe that their problem is not a problem "I only smoke pot".
The best place for you to go would be to a Doctor. List all of the "changes" and take it to a medical professional who will be more able to diagnose the condition and who will most likely have a list of other potential issues.
If you have solid grounds for meth:
baggies (tiny ziplock bags), rigs (hypodermic needles) a crack pipe (usually but not always a glass tube, sometimes in the shape of pipe. Sometimes just a tin foil or coke can with holes and indentations for smoking meth/crack). Small mirrors or glass (sometimes marble, sometimes metal) along with loose razorblades and either pens missing their ink and points or straws or paper rolled into tubes).
Then you most likely do have an addict on your hands. In that case I direct your attention to Alanon/alateen (I think alanon.org).
Alanon is Program for people who have addicts in their life.
It is a program for YOU not the addict or suspected addict. YOU (not your addict) goes to those meetings YOU (not the addict) learns how to handle the situation from the perspective of being a loved one of an addict.
It is a program for YOU not the addict.
Most of what they will tell you you will not like. Things like Tough Love, things like cut your loses and let the addict fall. Things like distance yourself from the addict.
You CANNOT save an addict from their addictions. I made that mistake.
BTW I am a member not only of Alanon/Alateen, I am also a chip carrying member of Alcoholics Anonymous and Narcotics Anonymous different programs for different problems. All that means is I know both sides of the issue when it comes to drugs.
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