Here's a list up to May 7, 2006: AMERICAN LEAGUE CAREER RBI RBI 1 Babe Ruth 2198 2 Lou Gehrig 1995 3 Ty Cobb 1933 4 Jimmie Foxx 1862 5 Carl Yastrzemski 1844 6 Ted Williams 1839 7 Al Simmons 1783 8 Rafael Palmeiro 1740 9 Reggie Jackson 1702 10 Cal Ripken 1695 11 Harold Baines 1628 12 Goose Goslin 1609 13 George Brett 1595 14 Harmon Killebrew 1584 15 Al Kaline 1583 T16 Tris Speaker 1537 T16 Joe DiMaggio 1537 18 Mickey Mantle 1509 19 Frank Thomas 1480 20 Jim Rice 1451 T21 Harry Heilmann 1442 T21 Eddie Murray 1442 T23 Yogi Berra 1430 T23 Manny Ramirez 1430 25 Charlie Gehringer 1427 26 Joe Cronin 1410 27 Jose Canseco 1407 28 Robin Yount 1406 29 Juan Gonzalez 1404 30 Dwight Evans 1384 31 Brooks Robinson 1357 32 Carlton Fisk 1330 33 Ruben Sierra 1313 34 Paul Molitor 1307 T35 Eddie Collins 1300 T35 Joe Carter 1300 37 Mickey Vernon 1296 38 Bob Johnson 1283 39 Don Baylor 1276 40 Sam Crawford 1264 41 Edgar Martinez 1261 42 Alex Rodriguez 1250 43 Bobby Doerr 1247 44 Albert Belle 1239 45 Bill Dickey 1209 T46 Dave Winfield 1207 T46 Bernie Williams 1207 48 Hank Greenberg 1202 49 Boog Powell 1182 50 Vic Wertz 1178 51 Vern Stephens 1174 52 Bobby Veach 1166 T53 Earl Averill 1163 T53 Willie Horton 1163 55 Tony Lazzeri 1154 T56 Ken Griffey Jr. 1152 T56 Rudy York 1152 58 Rocky Colavito 1148 59 Nap Lajoie 1141 60 Tino Martinez 1127 61 Cecil Cooper 1125 62 Luke Appling 1116 63 Norm Cash 1103 64 Don Mattingly 1099 65 Heinie Manush 1089 66 Fred Lynn 1088 T67 Kent Hrbek 1086 T67 Graig Nettles 1086 69 Kirby Puckett 1085 70 Lou Whitaker 1084 71 Sam Rice 1078 72 Gary Gaetti 1076 T73 B.J. Surhoff 1075 T73 Mike Higgins 1075 75 Brian Downing 1073 76 Jimmy Dykes 1071 77 Garret Anderson 1062 78 Jason Giambi 1061 79 Carlos Delgado 1058 T80 George Scott 1051 T80 Joe Sewell 1051 82 Joe Kuhel 1049 83 Sal Bando 1039 84 Joe Judge 1025 85 Travis Fryman 1022 86 Rod Carew 1015 87 Wade Boggs 1014 88 Minnie Minoso 1013 T89 Hal Trosky 1012 T89 Hal McRae 1012 91 Cecil Fielder 1008 92 Bob Meusel 1005 93 Alan Trammell 1003 94 Tim Salmon 995 95 Amos Otis 992 96 Bing Miller 990 97 Home Run Baker 987 98 Julio Franco 978 99 Mo Vaughn 977 100 Ivan Rodriguez 976 101 Joe Gordon 975 102 Larry Doby 970 103 Roy Sievers 969 104 Rickey Henderson 968 105 Del Pratt 966 106 Jay Buhner 965 107 George Sisler 961 T108 Ben Chapman 959 T108 Jim Thome 959 110 Chili Davis 954 111 Marty McManus 949