Yes, although rare, there have been reports that flashy video game visuals have caused seizures. Whats interesting is that there have been incidents where a tv show also caused seizures. In Japan, when the 'pokemon' Tv show had a flashy visual sequence where pikachu was electrocuting someone, children around the country were reported to have seizures. The good thing is there is no evidence that flashy video games can cause epilepsy. Read about video games and seizures here: http://www.epilepsy.com/info/family_kids_video.html excerpt from article: Reports in newspapers and on television have heightened public awareness that playing video games can, in rare cases, trigger seizures, but there is no scientific evidence that video games can cause epilepsy. Playing video games is an extremely common pastime for many children, and they often play them for long periods of time. Because epilepsy is a common disorder, it is not surprising that some children will have their seizures while playing video games, just by coincidence. How often this happens, and to what extent the games trigger the seizures, if at all, is not known. Read about the Pokemon incident that sent hundreds to the hospital: http://www.cnn.com/WORLD/9712/17/video.seizures.update/index.html article excerpt: Japanese cartoon triggers seizures in hundreds of children TOKYO (CNN) -- The bright flashing lights of a popular TV cartoon became a serious matter Tuesday evening, when they triggered seizures in hundreds of Japanese children. In a national survey, the Tokyo fire department found that at least 618 children had suffered convulsions, vomiting, irritated eyes, and other symptoms after watching "Pokemon." An interesting article about tv and video games causing seizures and also offers tips on how to prevent such seizures: http://www.webmd.com/content/Article/112/110307.htm?pagenumber=1 excerpts: Sept. 20, 2005 -- The Epilepsy Foundation has issued new guidelines to help avoid rare cases of seizures triggered by flickering lights from TV and video games. How to prevent... Video Games * Sit at least 2 feet away from the screen in a well-lit room. * Reduce the screen's brightness. * Don't let children play video games if they are tired. * Take frequent breaks and look away from the screen every once in a while. * Cover one eye while playing and regularly change which eye is covered. * Turn the game off if strange or unusual feelings develop.