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Free radicals consist of an atom or small group of atoms that are short one electron. This causes them to try and obtain an electron for the nearest stable molecule. The loss of one electron can cause significant changes in organic molecules generally, which in some instances can lead to permanent DNA damage or cell death.
Antioxidants react with and neutralize free radicals.
Highly reactive, oxygen-based molecules that oxidize and destroy whatever they come in contact with. A by-product of normal oxygen metabolism, caused when an oxygen molecule is produced with an uneven number of electrons from other molecules, most commonly found in DNA, lipids, cell walls, and cell interiors. The damage that results can be found in an array of aging symptoms, including less energetic cells, “mutant” or malformed cells produced from mangled DNA (leading to cancer), and wrinkles resulting from cross-linked collagen and elastin fibers. Sun, stress, poor nutrition, certain drugs (e.g. antibiotics), and smoking can all lead to free radical formation. Antioxidants interfere with the manufacture of free radicals or turn them into harmless alcohols by evening out their number of electrons.
Free radicals are atoms or groups of atoms with an odd (unpaired) number of electrons and can be formed when oxygen interacts with certain molecules. Once formed these highly reactive radicals can start a chain reaction, like dominoes. Their chief danger comes from the damage they can do when they react with important cellular components such as DNA, or the cell membrane. Cells may function poorly or die if this occurs. To prevent free radical damage the body has a defense system of antioxidants.
Antioxidants are molecules which can safely interact with free radicals and terminate the chain reaction before vital molecules are damaged. Although there are several enzyme systems within the body that scavenge free radicals, the principle micronutrient (vitamin) antioxidants are vitamin E, beta-carotene, and vitamin C. Additionally, selenium, a trace metal that is required for proper function of one of the body's antioxidant enzyme systems, is sometimes included in this category. The body cannot manufacture these micronutrients so they must be supplied in the diet.
Vitamin E : d-alpha tocopherol. A fat soluble vitamin present in nuts, seeds, vegetable and fish oils, whole grains (esp. wheat germ), fortified cereals, and apricots. Current recommended daily allowance (RDA) is 15 IU per day for men and 12 IU per day for women.
Vitamin C : Ascorbic acid is a water soluble vitamin present in citrus fruits and juices, green peppers, cabbage, spinach, broccoli, kale, cantaloupe, kiwi, and strawberries. The RDA is 60 mg per day. Intake above 2000 mg may be associated with adverse side effects in some individuals.
Beta-carotene is a precursor to vitamin A (retinol) and is present in liver, egg yolk, milk, butter, spinach, carrots, squash, broccoli, yams, tomato, cantaloupe, peaches, and grains. Because beta-carotene is converted to vitamin A by the body there is no set requirement. Instead the RDA is expressed as retinol equivalents (RE), to clarify the relationship. (NOTE: Vitamin A has no antioxidant properties and can be quite toxic when taken in excess.)
I could not resist this one!
we in England have a "different sense of humour" to those in usa a
bit like canada (can I say that on here....)
Free radicals are protesters that have not been locked up!
http://www.ssrichardmontgomery.net
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Comments
I'll keep sipping my green tea then!
by Crumb Eye on March 27th, 2006
Down with the antioxidant reactionaries! Free the molecular hostages!
by notmrjohn on March 29th, 2006
Crumb Eye - I like green tea too but there are so many other great antioxidants.
by Alatea on May 9th, 2006