by MedExpert on November 4th, 2007

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What is the prognosis for pituitary dwarfism?

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  • by MedExpert on November 4th, 2007

    MedExpert

    The prognosis for each type of dwarfism varies. A panhypopituitarism dwarf does not pass through the initial onset of adult sexual development (puberty) and never produces enough gonadotropic hormones to develop adult sexual function. These individuals also have several other medical conditions. Dwarfism due to only growth hormone deficiency has a different prognosis. These individuals do pass through puberty and mature sexually, however, they remain proportionately small in stature.

    If the individual is lacking only growth hormone then growth hormone replacement therapy can be administered. The success of treatment with growth hormone varies however. An increase in height of 4–6 in (10–15 cm) can occur in the first year of treatment. Following this first year, the response to the hormone is not as successful. Therefore the amount of growth hormone administered must be tripled to maintain this rate. Long-term use is considered successful if the individual grows at least 0.75 in (2 cm) per year more than they would without the hormone. However, if the growth hormone treatment is not administered before the long bones—such as the legs and arms—fuse, then the individual will never grow. This fusion is completed by adult age.

    Improvement for individuals with dwarfism due to other causes such as a tumor, varies greatly. If the dwarfism is due to deprevational causes, then removing a child from that environment should help to alleviate the problem.

    Source: The Gale Group. Gale Encyclopedia of Medicine, 3rd ed.";

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