• If you develop excess synovial fluid in your knee--commonly called fluid on the knee or knee joint effusion--the treatment focuses on dealing with the underlying disease or injury that caused the excess fluid.


    Your doctor may aspirate the knee to remove the immediate swelling. Aspiration refers to using a needle to remove the fluid from the joint. However, failing to treat the underlying problem means that the fluid is likely to return.


    If the cause of knee fluid is osteoarthritis, you doctor may aspirate and then inject a corticosteroid to treat the inflammation in the joint.


    If you have gout or pseudogout of the knee, uric acid crystals form in the joint, causing inflammation. Treatments may include corticosteroid injection or nonsteroidal anti-inflammatory drugs (NSAIDs), such as Motrin or Advil. Other drugs used to treat gout include colchicines, allopurinol and probenecid.


    If you have a knee infection, antibiotics can treat the infection. According to the Mayo Clinic, you may also need repeated joint aspiration or surgery.


    If you have a knee injury, treating the injury promptly and properly is important.


    In some situations, arthroscopic knee surgery may be necessary to repair damage inside the knee joint.


    Water on the Knee -- Treatments and Drugs

    Acute Knee Effusions: A Systematic Approach to Diagnosis

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