by 
The Curious Bag
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<h4 class="dechead">On One Hand: High fructose corn syrup foods are high caloric
Many foods containing high fructose corn syrup have a high amount of calories and little nutrition, according to Mayo Clinic nutritionist Katherine Zeratsky, so people are more likely to consume higher amounts of these foods. Many foods with high fructose corn syrup also contain trans fats, which is a factor in obesity rates.
On the Other: No evidence that HFCS contributes to obesity
New York City based nutritionist Tanya Zuckerbrot purports that table sugar and high fructose corn syrup contain the same ingredients, and the same amount of sweetness, so that high fructose corn syrup doesn't necessarily contribute to obesity more than regular table sugar. The American Journal of Clinical Nutrition claims that there is no evidence to support that high fructose corn syrup directly causes weight gain.
Bottom Line
There are several factors that contribute to obesity, and high fructose corn syrup is not the sole culprit of obesity. In small doses, high fructose corn syrup will probably not cause obesity if combined with exercise and a healthy diet.
Source:
Mayo Clinic: High-fructose corn syrup: What are the concerns?
Msnbc: High fructose corn syrup: How dangerous is it?
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