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While several sources report that moderate drinking--two glasses of alcohol a day for men, but just one for women--while taking Lexapro probably won't have any harmful repercussions, combining any antidepressant with alcohol is inherently dangerous.
Increased Depression
While Lexapro is an antidepressant, it affects the brain's chemistry, as do depressants such as alcohol. Lexapro users have reported feeling inordinately depressed, tired or unmotivated after drinking alcohol.
Mood Swings
Users have also reported feeling unaccountably annoyed or angry after drinking on various online antidepressant discussion forums.
Increased Effects
Lexapro users unfamiliar with how the drug affects their body or brain may find themselves suddenly more inebriated after drinking less alcohol than they usually drank before going on the antidepressant.
Decreased Inhibitions
Users of antidepressants similar to Lexapro have recalled drinking heavily before doing or saying things so out of character that they wouldn't have done them under the influence of alcohol alone.
Unpredictable Results
The most dangerous element of mixing Lexapro with alcohol is the fact that the interaction has not yet been studied in detail, largely because the result may be different for each individual. For this reason, the official site Lexapro.com recommends avoiding alcohol while taking the drug.
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