Tamoxifen, which goes by the generic name of nolvadex, is an oral anti-estrogen medication that has been prescribed for more than 30 years to fight breast cancer. According to Breastcancer.org, it is the most commonly prescribed selective estrogen receptor modulator on the market. The benefits of the drug outweigh the risks, according to the National Cancer Institute.

Significance

When breast cancer is said to be estrogen receptor-positive, this means that estrogen encourages the growth of the cancer cells. Tamoxifen counters the effects of the estrogen in the cells.

Features

Tamoxifen reduces the risk that breast cancer will return by 40 to 50 percent in postmenopausal women, according to Breastcancer.org. The drug also reduces the risk that cancer will appear in the other breast by approximately 50 percent. Studies have shown that the drug is effective when taken daily for five years, according to the National Cancer Institute.

Effects

For women of all ages, Tamoxifen can slow or stop the growth of breast cancer in the advanced stages. The drug is effective because it blocks the estrogen that can encourage the growth of cancerous cells in the breast.

Benefits

Even though Tamoxifen fights estrogen, it also acts like estrogen in some cases. This means that people taking the drug receive some of the same benefits that are derived from estrogen replacement therapy, including a reduced risk of osteoporosis and lower cholesterol.

Side Effects

Serious side effects of Tamoxifen include blood clots, strokes and uterine cancer. Because these conditions can be fatal, it is critical that you let your doctor know if you have a history of blood clots, stroke or heart attack. Also tell your doctor if you smoke, have diabetes or high blood pressure.

Source:

National Cancer Institute: Tamoxifen

Breastcancer.org: Tamoxifen

MedlinePlus: Tamoxifen