Women who are peri-menopausal should use progesterone cream according to their cycle. During the menstrual period on days one through seven, do not use progesterone cream. On days eight through 21, use 1/4 tsp. twice daily. On days 22 through 28, use 1/4 to 1/2 tsp. twice daily. Repeat the process at the beginning of your next cycle.

On the Other: Menopausal Symptoms

Women who are menopausal have not had a menstrual period for at least 12 consecutive months. Similarly, surgically induced menopausal women no longer menstruate. Do not use the progesterone cream on days one through seven. On days eight through 30 or 31, use 1/8 to 1/4 tsp. twice daily. Because menopausal women no longer menstruate, they may base their scheduled start day on whichever calendar day is convenient.

Bottom Line

Always follow the manufacturer's recommendations for specific product dosage, which vary among available formulations. In addition, consult your medical professional before using progesterone cream. Perimenopausal women experiencing changes in their menstrual periods might benefit from progesterone cream. Menopausal women suffering from vasomotor symptoms and bloating may find relief from bioidentical hormone cream.

Source:

Emerita website: Product Information Progesterone

Women to Women website: Bioidentical Hormone Replacement Therapy Options

Resource:

Women's Health Initiative- NIH