Arrangement

Configuration refers to the arrangement of things, parts of things, or elements in a particular form, figure, shape, etc. For example, the configuration of the math problem was such that it couldn't be solved.

Position

In astronomy configuration is the relative position, apparent or actual, of planets or other celestial bodies. The configuration of our solar system, for example, places the sun at the center, and the planets orbiting around it.

Structure

In organic chemistry, it is the structure of compounds that is fixed by the chemical bonding in a molecule and cannot be altered without breaking the bonds.

Design

When referring to computers, the word configuration denotes the whole or totality of the computer and the devices connected to it. A common personal computer configuration includes a monitor, disk drive and printer.

Perception

In Gestalt psychology, a school of psychology which calls perceptions and reactions Gestalts, a configuration is an object of perception that forms a specific whole or unity incapable of expression simply in terms of its parts. For example, a melody derived from individual notes is a configuration.

Source:

Oxford English Dictionary

Dictionary.com