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by jillbert2 on November 29th, 2009

jillbert2

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Two antibiotics tested for their efficacy against a single bacterial species .If antibiotic A and antibiotic B produce zones of inhibition with the same diameter, how can the bacterium considered resistant to antibiotic A, but sensitive to antibiotic B?

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  • by Abdullah on December 1st, 2009

    Abdullah

    Simply that depends on the antibiotic amount !
    Because the inhibition zones describes how much antibiotic must used to kill the bacteria !
    or the bacteria could be mutated ! (if they are old colonys).

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  • by Anonymous on November 29th, 2009

    Anonymous

    Zones of inhibition vary by the antibiotic used.

    The zone of inhibition describes how much bacteria a given antibiotic can kill. But different antibiotics have different safe doses. Maybe a person can take 100mg of antibiotic A each day, but only 10mg of antibiotic B. Antibiotic A might result in a high enough concentration in human tissues to kill the bacteria (because you're taking more of it), where antibiotic B would be insufficient. In other words, even though they're equally effective at killing the bacteria when they're at equal concentrations, one is safe to give at much higher concentrations.

    There are charts that list the standard zones of inhibition for various antibiotics. When you test an antibiotic on bacteria, a larger-than-standard Zone means that the bacteria is sensitive to that antibiotic and a smaller zone indicates resistance.

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