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by failed_stoic on April 18th, 2009

failed_stoic

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Should people who believe that animals are accurate predictors of a human physiological reaction for a medicinal compound or procedure be the first humans to take that medication after it is found safe and effective in at least one other species?

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Answers. 3 helpful answers below.

  • by failed_stoic on October 26th, 2009

    failed_stoic

    response to 1st answer:
    Actually, the first clinical (human) trials fall under the rubric of “Phase 1” studies. These studies ordinarily involve the initial administration of the test drug to 20 through 80 healthy people. These studies are designed to determine the metabolism and other physiological human reactions to the drug. Effectiveness metrics for humans are incidental to Phase 1 trials. Source: A Practical Guide to Food and Drug Law and Regulation – 2nd ed., 2002.
    …
    This question has nothing to do with the industry’s power to use animals for business growth. It is quite obvious that they do have such power. It has everything to do with questioning if veterinary medicine data is dangerously misleading when applied to humans. Like you said, I am also “afraid animlas [sic] will remain an important part of medical investigation” even if it is only to safeguard revenue streams and bolster immunity from liability.

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  • by moonkiera on October 26th, 2009

    moonkiera

    Well you see, you can't give the meds to just anyone.

    The people who developed them most likely wouldn't be candidates for the human stage investigation because even thought a part is carried on healthy humans, the most important part has to take part on people who are sick, thus knowing if the pharmaceutic they have developed actually does what it is supposed to do.

    I'm guessing this question is related to the "is right to use animals as our test subjects", but the medical and pharmaceutical field are really complicated and a whole lot of experimental procedures are blocked due ethical reasons. So, for now at least until science is able to find a new way to test drugs and procedures, I'm afraid animlas will remain an important part of medical investigation.

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  • by Im Alec has abandoned this account on May 10th, 2010

    Im Alec has abandoned this account

    Only if people who believe that no testing is better than imperfect testing are the first to try totally untested medicines.

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