ANSWERS: 1
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It's very close to your starting safe house. Leave the house, take the alley right next to it and turn right. Denise's place is the first one on the right after the crossing. You can walk it if need be. She is usually available from 16:00 to 06:00. You do need to complete the "Burning Desires" mission in Los Santos first though (the first "Crash" mission, ordered by the bad cop Frank Tenpenny. I don't know why you ask, all the girlfriend's houses are clearly situated on your map by a heart.
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