Ask a Question
or
Create a Poll
  1. Home /
  2. Questions /
  3. Health
  4. / Drugs And Medicine
  5. / Prescription Drugs

by Ruby21103 on December 15th, 2006

Ruby21103

Question

Help answer this question below.

Why can't I drink grapefriut juice or eat grapefruit while on Xanax?

  • Like
  • Report
Share:
Other

Answers. 12 helpful answers below.

  • by Drublic on December 15th, 2006

    Drublic

    Grapefruit juice slows the body's normal breakdown of several drugs, including some benzodiazepines, allowing them to build up to potentially dangerous levels in the blood. A recent study indicates this effect can last for 3 days or more following the last glass of juice.

    Because of this risk, if you take benzodiazepines, the safest approach is to avoid grapefruit juice altogether.

    http://www.healthboards.com/boards/showthread.php?t=145765&highlight=halcion

    • Like
    • Report

    No comments. Post one | Permalink

  • by mejinn on March 18th, 2007

    mejinn

    There is an enzyme in grapefruit juice that prevents xanax from being effectively metabolized and decreases absorption therby lessening its effects.

    • Like
    • Report

    2 comments | Post one | Permalink

  • by Mirage V2.0 AWOL on December 16th, 2006

    Mirage V2.0 AWOL

    There is a chance for side effects as mentioned previously.

    If you are seeking to enhance the drugs strength and effect, you will not notice the difference, but your body may react a day or two later when you fall asleep at the wheel.

    • Like
    • Report

    No comments. Post one | Permalink

  • by Amanda on April 6th, 2009

    Amanda

    The first per that answered you question is totally false! However the rest of the answeres are right on point.

    • Like
    • Report

    No comments. Post one | Permalink

  • by Go know thyself is THE RED QUEEN on January 2nd, 2009

    Go know thyself is THE RED QUEEN

    Grapefruit juice messes with lots of drugs.

    Depending on where the drug is metabolized. Some are effective while in the stomach some in the intestines.

    It causes the absorption of the active ingredient to slow. Which could cause you to over dose more easily.

    • Like
    • Report

    3 comments | Post one | Permalink

  • by BEARBOI on January 2nd, 2009

    BEARBOI

    I need to know why I cannot take my Xanax 2mg with Grapefruit juice. I love my Salty dogs and need to know if this will just increase the effects of the Xanax by just a little or will it be life threatening! I usually take 2mg when I feel my panic attacks are coming along. Any info is helpful, if this only increases the effect, i won't worry because I need the extra kick from the xanax! I'm no druggie but need the relief from my job loss, father dying, etc.

    • Like
    • Report

    No comments. Post one | Permalink

  • by JIMDSWEENEY on November 9th, 2008

    JIMDSWEENEY

    Thisis a Link from a med journal

    http://www.ncbi.nlm.nih.gov/pubmed/8856830?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed

    Here was the conclusion to the study...

    Although the combined effects were not distinguishable in terms of additivity or independence in both the DRCs and in the behavior-time profiles, they showed neither synergism nor antagonism. The pharmacokinetics of alprazolam were not altered by caffeine, but those of caffeine were affected by alprazolam.

    • Like
    • Report

    No comments. Post one | Permalink

  • by jenniferx on January 8th, 2007

    jenniferx

    it supposedly increases the effects of it. it just make you sleepier. well, it does me but i've been taking it for years.

    • Like
    • Report

    No comments. Post one | Permalink

  • by germaster on December 16th, 2006

    germaster

    i love both grapefruit juice and xanax, but never mixed, grapefruit juice also goes great with vodka.

    • Like
    • Report

    No comments. Post one | Permalink

  • by GARY MARSHALL on December 15th, 2006

    GARY MARSHALL

    It intensifies the effects.

    • Like
    • Report

    2 comments | Post one | Permalink

  • by fredhetz on December 15th, 2006

    fredhetz

    Very interesting question -- I was not aware of this sort of problem.

    Note that "alprazolam" is the generic name for "Xanax."

    A clinical study shows that grapefruit juice has a weak interaction with alprazolam containing drugs. However, it is unlikely that the effect of grapefruit juice on the efficacy and safety of alprazolam would be clinically relevant. If you are taking medication in this drug category that has a strong or moderate interaction with grapefruit juice and would like to continue drinking grapefruit juice, please ask your physician if alprazolam could be an option for you.

    • Like
    • Report

    No comments. Post one | Permalink

  • by Endlessgemini on October 1st, 2007

    Endlessgemini

    I don't know, but would love to find out the real reason.

    No comments. Post one | Permalink

Want to attach an image to your answer? Click here.

Did this answer your question? If not, then ask a new question or create a poll.

More Questions. Additional questions in this category.

You're reading Why can't I drink grapefriut juice or eat grapefruit while on Xanax? - which can also be phrased in the following ways:

  • How does grapefruit juice affect the drug xanax

Follow us on Facebook!

Related Ads

Related Questions

Professionally Researched

ANSWERBAG BUZZ

Xanax and grapefruit juice
Grapefruit juice and xanax
Xanax grapefruit juice
Xanax and grapefruit interaction
Grapefruit juice xanax

Answerbag

a Demand Media company