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Actos

Generic Name: Pioglitazone (PYE-oh-GLI-ta-zone)
Brand Name: Actos

Actos is used for:


Treating type 2 diabetes in certain patients. It is used along with diet and exercise. It may be used alone or with other antidiabetic medicines.

Actos is a thiazolidinedione antidiabetic. It works by lowering blood sugar by making the cells of the body more sensitive to the action of insulin.


Before using Actos:

Some medical conditions may interact with Actos. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have diabetic ketoacidosis (a severe problem associated with diabetes)
if you have a history of liver problems, abnormal liver function tests, heart problems (eg, congestive heart failure [CHF]), or eye or vision problems
if you have swelling problems (edema)

Some MEDICINES MAY INTERACT with Actos. Tell your health care provider if you are taking any other medicines, especially any of the following:
Gemfibrozil, insulin, or oral antidiabetic medicines (eg, glipizide) because the risk of low blood sugar may be increased
Rifampin because it may decrease Actos's effectiveness, resulting in high blood sugar
Anticoagulants (eg, warfarin) because the risk of their side effects may be increased or their effectiveness may be decreased by Actos

This may not be a complete list of all interactions that may occur. Ask your health care provider if Actos may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Actos:

Use Actos as directed by your doctor. Check the label on the medicine for exact dosing instructions.
An extra patient leaflet is available with Actos. Talk to your pharmacist if you have questions about this information.
Take Actos by mouth with or without food.
Continue to take Actos even if you feel well. Do not miss any doses.
Taking Actos at the same time each day will help you remember to take it.
If you miss a dose of Actos, take it as soon as possible. If it almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Actos.


Possible side effects of Actos:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; muscle aches; sore throat; weight gain.
Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; symptoms of heart failure (eg, shortness of breath; sudden unexplained weight gain; swelling of the hands, ankles, or feet); symptoms of liver problems (eg, dark urine; stomach pain; unexplained nausea, vomiting, or loss of appetite; yellowing of the skin or eyes; sweating); symptoms of low blood sugar (eg, anxiety; chills, increased hunger, headache; increased dizziness or drowsiness; tremors); unusual bone pain; unusual tiredness or weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.


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