I have been told we have brown recluse spiders in our house. The pest control guy is spraying for them tomorrow but I worry about being bit..has anyone ever been bit by a brown recluse?

Bite Symptoms
The physical reaction to a brown recluse spider bite depends on the amount of venom injected and an individual's sensitivity to it. Some people are unaffected by a bite, whereas others experience immediate or delayed effects as the venom kills the tissues (necrosis) at the site of the bite. Many brown recluse bites cause just a little red mark that heals without event. The vast majority of brown recluse bites heal without severe scarring (http://spiders.ucr.edu/avoidbites.html).

Initially, the bite may feel like a pinprick or go unnoticed. Some may not be aware of the bite for 2 to 8 hours. Others feel a stinging sensation followed by intense pain. Infrequently, some victims experience general systemic reactions that may include restlessness, generalized itching, fever, chills, nausea, vomiting, or shock. A small white blister usually initially rises at the bite site surrounded by a swollen area. The affected area enlarges and becomes red, and the tissue is hard to the touch for some time. The lesion from a brown recluse spider bite is a dry, blue-gray or blue-white, irregular sinking patch with ragged edges and surrounding redness--termed the "red, white, and blue sign." The lesion usually is 1½ inches by 2¾ inches or smaller. Characteristics of a bite are further discussed at http://www.amednews.com/free/hlsa0805.

The bite of the brown recluse spider can result in a painful, deep wound that takes a long time to heal. Fatalities are extremely rare, but bites are most dangerous to young children, the elderly, and those in poor physical condition. When there is a severe reaction to the bite, the site can erupt into a "volcano lesion" (a hole in the flesh due to damaged, gangrenous tissue). The open wound may range from the size of an adult's thumbnail to the span of a hand. The dead tissue gradually sloughs away, exposing underlying tissues. The sunken, ulcerating sore may heal slowly up to 6 to 8 weeks. Full recovery may take several months and scarring may remain.

It is difficult for a physician to accurately diagnose a "brown recluse bite" based simply on wound characteristics. It is absolutely necessary to have the spider for a positive identification. Necrotic wounds can result from a variety of agents such as bacteria (Staphylococcus, "flesh-eating" Streptococcus, etc.), viruses, fungi, and arthropods (non-recluse spiders, centipedes, mites, ticks, wasps, bedbugs, kissing bugs, biting flies, etc.). Necrotic conditions also can be caused by vascular and lymphatic disorders, drug reactions, underlying diseases states, and a variety of other agents. An annotated list of conditions that could be mistaken for a brown recluse spider bite is available at http://www.ama-assn.org/amednews/2002/08/05/hlsa0805.htm. Misdiagnosis of lesions as brown recluse bites can delay appropriate care.

First Aid
If bitten, remain calm, and immediately seek medical attention (contact your physician, hospital and/or poison control center). Apply an ice pack directly to the bite area to relieve swelling and pain. Collect the spider (even a mangled specimen has diagnostic value), if possible, for positive identification by a spider expert. A plastic bag, small jar, or pill vial is useful and no preservative is necessary, but rubbing alcohol helps to preserve the spider.

An effective commercial antivenin is not available. The surgical removal of tissue was once standard procedure, but now this is thought to slow down wound healing. Some physicians administer high doses of cortisone-type hormones to combat hemolysis and other systemic complications. Treatment with oral dapsone (an antibiotic used mainly for leprosy) has been suggested to reduce the degree of tissue damage. However, an effective therapy has not yet been found in controlled studies.

http://ohioline.osu.edu/hyg-fact/2000/2061.html

(This is a very good site. I would recommend reading it.)